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Trigonelline in minimizing oxidative stress Moreover, trigonelline was found to minimize oxidative stress by boosting antioxidant enzyme activity and have a scavenging effect on ROS in a study conducted on rats (Zhou et al., 2013)

Acknowledgements The authors' research is supported by grants from the Swedish Research Council

It is understood that this is a result of long-range allosteric interactions between the methionine cycle and the folate cycle [18]